Master Amino Acid Pattern (MAP) and The Discovery of the Ideal Amino Acid Pattern for Human Nutrition
The Nutritional Failure of Amino Acid Formulations
The nutritional failure of amino acid formulations generated, among the scientific community, even more discrepancies and raised confusion over several basic questions:
- How many amino acids are essential for human nutrition?
- What is the "ideal" combination of amino acids for human nutrition?
- How can the daily requirement of amino acids be calculated?
- Should an amino acid mixture provide only the essential amino acids or also the non-essential amino acids? (And in what proportion?)
Years later, these questions were finally answered and confirmed after approximately two decades of research. Shortcomings of the previous research methodologies were found and remedied. The result: the discovery of the ideal amino acid pattern for human nutrition.
This pattern is comprised of unique proportions of essential amino acids. Now for the first time in medical history it is possible to provide protein nutritional support that releases virtually no nitrogen waste or calories.
Understanding Protein Nutritional Values
From a nutritional point of view, the most important aspect of proteins is their amino acid composition. Amino acids from a dietary protein or an amino acid supplement are absorbed in the small intestine. These amino acids then can follow either the anabolic pathway ( build-up ) or the catabolic pathway ( breakdown ). To illustrate:

When dietary amino acids follow the catabolic pathway , they act only as a source of energy and not as "building blocks." Throughout the catabolic pathway , amino acids release unwanted nitrogen catabolites.
On the other hand, when dietary amino acids follow the anabolic pathway, they act as precursors or "building blocks" in the body's protein synthesis. Throughout the anabolic pathway, amino acids do not release any nitrogen catabolites (metabolic waste) or calories.
The percentage of the total amino acids in a dietary protein or amino acid formula that are used as "building blocks" represents the protein nutritional value and is known as Net Nitrogen Utilization (NNU) .



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