Master Amino Acid Pattern (MAP) and The Discovery of the Ideal Amino Acid Pattern for Human Nutrition
The Protein Buffer System
For proteins to function properly, stable pH and temperature are required. The delicate shapes of proteins can be affected (or denatured) by excessive fever or excessive pH (to acidic or basic).
Amino acids can accept or donate hydrogen ions, making them excellent buffers. Since proteins are made up of amino acids, proteins themselves can act as buffers.
(Amino acids have a central carbon group with four groups attached:
- a carboxyl group (COOH)
- an amino group (NH2)
- a hydrogen atom
- an R group
The carboxyl group and amino groups are what enable proteins to act as buffers.)
Proteins are found in very high concentration intracellular solutions and in blood. Of the three important buffering systems in the body — the bicarbonate buffer system, the phosphate buffer system and the protein buffer system — the protein buffering system is considered the most powerful.
Maintaining Normal Protein Synthesis
Proteins play a role in all physiological processes, and all processes can be affected by inadequate protein synthesis.
After the discovery of the ideal amino acid pattern for human nutrition, for the first time all individuals, regardless of age or health status, can safely meet their protein requirements without stressing kidney and liver functions. Individuals can now safely, easily, and more effectively maintain normal protein synthesis, especially as they age.
The loss of lean-tissue begins around the age of 25 and usually becomes noticeable by the age of 45. This process can occur even in the absence of weight loss or illness. (Muscle is the major source of protein for functions such as anti-body production, would healing, and white blood cell production during illness. If the body's protein reserves are already depleted, there is less to mobilize for illness. )
The degree of the loss of lean-tissue will vary among individuals, and its effects can range from a mild loss of tissue firmness, skin elasticity, and stamina to a significant loss of tissue integrity and function.
It is important to help individuals understand the relationship between inadequate protein synthesis and a diminishing quality of life. Adequate protein synthesis helps support:
- Immune function
- Heart and bone cell turnover rates
- Red blood cell production
- Muscle tone
- PH and fluid balance, etc.
A loss of body protein means a loss of function.
The value of maintaining normal protein synthesis cannot be overstated for anyone at any age. In clinical practice, it is extremely common to see individuals who, for various reasons, are not meeting their daily protein/amino acid requirements.
A formula that contains the ideal amino acid pattern for human nutrition is the safest most effective nutritional support. Thus, it can be used to help individuals of any age meet their daily protein/amino acid requirements.
Additional information and references are available from drminkoff@optimumhealthreport.com
This article was originally published in Explore! For the Professional, Volume 12, Number 6, 2003 by David I. Minkoff, M.D., Medical Director of Bodhealth.com Inc., and Linda Christian, N.D.; USA.
Champe P.C., Harvey R.A., "Lippincott's Illustrated Reviews: Biochemistry." — 2 nd ed. Page 1. J.B. Lippincott Company, Philidelphia 1994.
Matthew, Dwight E., in "Modern Nutrition in Health and Disease" Shils, M.E., Olson, J.A. (et al.). — 9 th ed. (Eds), pag 21-22. Lippincott Williams & Wilkins, Philadelphia 1999.
Roubenoff B, Castenada C. Sarcopenia—Understanding the Dynamics of Aging Muscle. JAMA 2001; 286: 1230.

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